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Article

Single nucleotide polymorphisms in TNFSF15 confer susceptibility to Crohn's disease.

Human molecular genetics - 15 Nov 2005

Yamazaki Keiko, McGovern Dermot, Ragoussis Jiannis, Paolucci Marta, Butler Helen, Jewell Derek, Cardon Lon, Takazoe Masakazu, Tanaka Torao, Ichimori Toshiki, Saito Susumu, Sekine Akihiro, Iida Aritoshi, Takahashi Atsushi, Tsunoda Tatsuhiko, Lathrop Mark, Nakamura Yusuke

Abstract excerpt

The inflammatory bowel diseases (IBDs), Crohn's disease (CD) and ulcerative colitis, are chronic inflammatory disorders of the digestive tract. The pathogenesis of IBD is complicated, and it is widely accepted that immunologic, environmental and genetic components contribute to its etiology. To identify genetic susceptibility factors in CD, we performed a genome-wide association study in Japanese patients and...

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Source

Identifiers

PMID: 16221758
DOI: 10.1093/hmg/ddi379

Genes

TNFSF15

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Single nucleotide polymorphisms in TNFSF15 confer susceptibility to Crohn's disease.PMID 16221758Read ↗

Association of TNFSF15 with Crohn's disease in Koreans.Semantic proximity Read ↗

Contribution of TNFSF15 gene variants to Crohn's disease susceptibility confirmed in UK population.Semantic proximity Read ↗

Associations between TNFSF15 polymorphisms and susceptibility to ulcerative colitis and Crohn's disease: A meta-analysis.Semantic proximity Read ↗

TNFSF15 polymorphisms are associated with susceptibility to inflammatory bowel disease in a new European cohort.Semantic proximity Read ↗

Association of TNFSF15 polymorphisms in Korean children with Crohn's disease.Semantic proximity Read ↗

Polymorphism rs6478109 in the TNFSF15 gene contributes to the susceptibility to Crohn's disease but not ulcerative colitis: a meta-analysis.Semantic proximity Read ↗

Protective association of TNFSF15 polymorphisms with Crohn's disease and ulcerative colitis: A meta-analysis.Semantic proximity Read ↗

Protective association of tumor necrosis factor superfamily 15 (TNFSF15) polymorphic haplotype with Ulcerative Colitis and Crohn's disease in an Indian population.Semantic proximity Read ↗

TNFSF15 is an independent predictor for the development of Crohn's disease-related complications in Koreans.Semantic proximity Read ↗

A genome-wide association study identifies 2 susceptibility Loci for Crohn's disease in a Japanese population.Semantic proximity Read ↗

Population-specific susceptibility to Crohn's disease and ulcerative colitis; dominant and recessive relative risks in the Japanese population.Semantic proximity Read ↗

Confounding effects of microbiome on the susceptibility of TNFSF15 to Crohn's disease in the Ryukyu Islands.Semantic proximity Read ↗

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