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Article

Beta amyloid oligomers and fibrils stimulate differential activation of primary microglia.

Journal of neuroinflammation - 5 Jan 2009

Sondag Cindy M, Dhawan Gunjan, Combs Colin K

Abstract excerpt

BACKGROUND: Beta amyloid (Abeta) peptides are the major constituents of the senile plaques present in Alzheimer's diseased brain. Pathogenesis has been associated with the aggregated form of the peptide as these fibrils are the conformation readily found in the plaques. However, recent studies have shown that the nonaggregated, soluble assemblies of Abeta have the potential to stimulate neuronal dysfunction and...

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Identifiers

PMID: 19123954
DOI: 10.1186/1742-2094-6-1
PMCID: PMC2632990

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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