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Microglia in Alzheimer's Disease: A Role for Ion Channels

28 Sept 2018

Abstract excerpt

Alzheimer's disease is the most common form of dementia, it is estimated to affect over 40 million people worldwide. Classically, the disease has been characterized by the neuropathological hallmarks of aggregated extracellular amyloid-β and intracellular paired helical filaments of hyperphosphorylated tau. A wealth of evidence indicates a pivotal role for the innate immune system, such as microglia, and...

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PMID: 30323735
DOI: 10.3389/fnins.2018.00676

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