Article
The impact of neuroimmune changes on development of amyloid pathology; relevance to Alzheimer's disease.
Immunology - 1 Mar 2014
Lynch Marina A
Abstract excerpt
Neuroinflammatory changes are a characteristic of several, if not all, neurodegenerative diseases including Alzheimer's disease and are typified by increased microglial activation. Microglia express several receptors making them highly reactive and plastic cells, and, at least in vitro, they adopt different phenotypes in a manner analogous to their peripheral counterparts, macrophages. Microglia also express...
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