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Article

The ACE gene I/D polymorphism does not affect the susceptibility to or prognosis of PBC.

The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology - 1 Dec 2008

Oruç Nevin, Lamb Janette, Whitcomb David J, Sass David A

Abstract excerpt

BACKGROUND/AIMS: Primary biliary cirrhosis is an autoimmune liver disease that is strongly influenced by poorly defined, complex genetic factors. Alterations of the renin-angiotensin system have been implicated in the pathogenesis of various diseases. A deletion polymorphism of a 287-bp fragment of intron 16 of the angiotensin converting enzyme gene allele results in higher levels of circulating enzyme....

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PMID: 19119484

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ACE

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