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Article

Angiotensin-converting enzyme insertion/deletion polymorphism in patients with acute and chronic pancreatitis.

European journal of gastroenterology & hepatology - 1 Sept 2009

Hucl Tomas, Kylanpää Marja-Leena, Künzli Beat, Witt Heiko, Lempinen Marko, Schneider Alexander, Kemppainen Esko, Löhr Matthias, Haas Stephan L, Friess Helmut, Ockenga Johann, Rosendahl Jonas, Schulz Hans-Ulrich, Gress Thomas, Singer Manfred V, Pfützer Roland H

Abstract excerpt

BACKGROUND: Reduction in angiotensin-converting enzyme (ACE) activity has been shown to attenuate pancreatic stellate cell activation and pancreatic fibrosis and suggested as a potential treatment for chronic pancreatitis. The ACE gene insertion/deletion (I/D) polymorphism in intron 16 accounts for nearly half the variation in serum ACE levels. This study determined the frequency of the I/D polymorphism in...

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Identifiers

PMID: 19307975
DOI: 10.1097/MEG.0b013e328326f586

Genes

ACE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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