Article
Major histocompatibility complex class-II alleles in primary biliary cirrhosis.
Scandinavian journal of immunology - 1 Jan 1994
Zhang L, Weetman A P, Bassendine M, Oliveira D B
Abstract excerpt
The major histocompatibility complex (MHC) class-II alleles at the DRB1, DQB1 and DPB1 loci were investigated in 40 patients with primary biliary cirrhosis (PBC) and 43 local healthy controls. Restriction fragment length polymorphism (RFLP) was used for DRB1 typing. DQB1 and DPB1 regions were amplified using the polymerase chain reaction (PCR) and then probed with 32P-labelled allele-specific oligonucleotide...
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