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Article

Efficacy of short-course AZT plus 3TC to reduce nevirapine resistance in the prevention of mother-to-child HIV transmission: a randomized clinical trial.

PLoS medicine - 1 Oct 2009

McIntyre James A, Hopley Mark, Moodley Daya, Eklund Marie, Gray Glenda E, Hall David B, Robinson Patrick, Mayers Douglas, Martinson Neil A

Abstract excerpt

BACKGROUND: Single-dose nevirapine (sdNVP)-which prevents mother-to-child transmission of HIV-selects non-nucleoside reverse-transcriptase inhibitor (NNRTI) resistance mutations in the majority of women and HIV-infected infants receiving it. This open-label, randomised trial examined the efficacy of short-course zidovudine (AZT) and lamivudine (3TC) with sdNVP in reducing NNRTI resistance in mothers, and as a...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Infectious Disease Transmission, Vertical

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Source

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Identifiers

PMID: 19859531
DOI: 10.1371/journal.pmed.1000172
PMCID: PMC2760761

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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