Article
Analysis of nevirapine (NVP) resistance in Ugandan infants who were HIV infected despite receiving single-Dose (SD) NVP versus SD NVP plus daily NVP up to 6 weeks of age to prevent HIV vertical transmission.
The Journal of infectious diseases - 1 Oct 2008
Church Jessica D, Omer Saad B, Guay Laura A, Huang Wei, Lidstrom Jessica, Musoke Philippa, Mmiro Francis, Jackson J Brooks, Eshleman Susan H
Abstract excerpt
BACKGROUND: Single-dose nevirapine (SD NVP) at birth plus NVP prophylaxis for the infant up to 6 weeks of age is superior to SD NVP alone for prevention of vertical transmission of human immunodeficiency virus (HIV) through breastfeeding. We analyzed NVP resistance in HIV-infected Ugandan infants who received either SD NVP or extended NVP prophylaxis. METHODS: We tested plasma HIV by using a genotyping assay...
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