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Article

Normal feeding and body weight in Fischer 344 rats lacking the cholecystokinin-1 receptor gene.

Brain research - 19 Feb 2009

Blevins J E, Overduin J, Fuller J M, Cummings D E, Matsumoto K, Moralejo D H

Abstract excerpt

A large body of evidence has demonstrated that one mechanism by which cholecystokinin (CCK) inhibits food intake through activation of CCK1 receptors (CCK1R) on vagal afferent neurons that innervate the gastrointestinal tract and project to the hindbrain. OLETF rats, which carry a spontaneous null mutation of the CCK1R, are hyperphagic, obese, and predisposed to type 2 diabetes. Recently, by introgressing the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 19111529
DOI: 10.1016/j.brainres.2008.12.015
PMCID: PMC6202117

Genes

CCK

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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