Article
Endogenous prolactin-releasing peptide regulates food intake in rodents.
The Journal of clinical investigation - 1 Dec 2008
Takayanagi Yuki, Matsumoto Hirokazu, Nakata Masanori, Mera Takashi, Fukusumi Shoji, Hinuma Shuji, Ueta Yoichi, Yada Toshihiko, Leng Gareth, Onaka Tatsushi
Abstract excerpt
Food intake is regulated by a network of signals that emanate from the gut and the brainstem. The peripheral satiety signal cholecystokinin is released from the gut following food intake and acts on fibers of the vagus nerve, which project to the brainstem and activate neurons that modulate both gastrointestinal function and appetite. In this study, we found that neurons in the nucleus tractus solitarii of the...
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