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Article

Normal food intake and body weight in mice lacking the G protein-coupled receptor GPR39.

Endocrinology - 1 Feb 2007

Tremblay Frédéric, Perreault Mylène, Klaman Lori D, Tobin James F, Smith Erica, Gimeno Ruth E

Abstract excerpt

It has been recently proposed that obestatin, a peptide encoded by the ghrelin gene, reduces food intake by activating the orphan G protein-coupled receptor GPR39. To gain further insights into the role of GPR39 in body weight homeostasis, we characterized the phenotype of mice with targeted disruption of the GPR39 gene. Body weight, adiposity, and food intake were found to be similar between GPR39(+/+) and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 17095592
DOI: 10.1210/en.2006-1275

Genes

GPR39

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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