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Article

Structural characterizations of glycerol kinase: unraveling phosphorylation-induced long-range activation.

Biochemistry - 20 Jan 2009

Yeh Joanne I, Kettering Regina, Saxl Ruth, Bourand Alexa, Darbon Emmanuelle, Joly Nathalie, Briozzo Pierre, Deutscher Josef

Abstract excerpt

Glycerol metabolism provides a central link between sugar and fatty acid catabolism. In most bacteria, glycerol kinase plays a crucial role in regulating channel/facilitator-dependent uptake of glycerol into the cell. In the firmicute Enterococcus casseliflavus, this enzyme's activity is enhanced by phosphorylation of the histidine residue (His232) located in its activation loop, approximately 25 A from its...

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Identifiers

PMID: 19102629
DOI: 10.1021/bi8009407
PMCID: PMC3158585

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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