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Structure, Mutation, Functional Domain Roles and Medical Implications of Glycerol Kinase.

The protein journal - 1 Feb 2026

Balogun Emmanuel Oluwadare, Ogra Israel Ogwuche, Ndidi Uche Samuel, Tizhe Daniel Thakuma, Iroha Okechukwu Kalu, Ebiloma Godwin Unekwuojo, Jeelani Ghulam, Nozaki Tomoyoshi, Siqueira-Neto Jair, De Koning Harry P, Shiba Tomoo

Abstract excerpt

Glycerol kinase (GK) is a key part of glycerol metabolism. It connects the metabolic pathways for lipids and carbohydrates by phosphorylating glycerol to glycerol-3-phosphate in an ATP-dependent reaction. This is essential for maintaining carbohydrate homeostasis, plasma glycerol withdrawal, and the utilization of glycerol by different tissues. Together, these processes impact glucose uptake and lipid metabolism....

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Enzyme Inhibitors
Glycerol
Lipid Metabolism
Models, Molecular
Mutation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Protein Domains

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PMID: 41537922
DOI: 10.1007/s10930-025-10316-2

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GK

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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Structure, Mutation, Functional Domain Roles and Medical Implications of Glycerol Kinase.PMID 41537922Read ↗

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