Article
Temporal analysis of ectopic enamel production in incisors from sprouty mutant mice.
Journal of experimental zoology. Part B, Molecular and developmental evolution - 15 Jul 2009
Boran Tomas, Peterkova Renata, Lesot Herve, Lyons David B, Peterka Miroslav, Klein Ophir D
Abstract excerpt
The mouse incisor has two unusual features: it grows continuously and it is covered by enamel exclusively on the labial side. The continuous growth is driven in part by epithelial stem cells in the cervical loop region that can both self-renew and give rise to ameloblasts. We have previously reported that ectopic enamel is found on the lingual side of the incisor in mice with loss-of-function of sprouty (spry)...
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