Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Regulation of mammalian tooth cusp patterning by ectodin.

Science (New York, N.Y.) - 23 Sept 2005

Kassai Yoshiaki, Munne Pauliina, Hotta Yuhei, Penttilä Enni, Kavanagh Kathryn, Ohbayashi Norihiko, Takada Shinji, Thesleff Irma, Jernvall Jukka, Itoh Nobuyuki

Abstract excerpt

Mammalian tooth crowns have precise functional requirements but cannot be substantially remodeled after eruption. In developing teeth, epithelial signaling centers, the enamel knots, form at future cusp positions and are the first signs of cusp patterns that distinguish species. We report that ec...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bone Morphogenetic Protein 4
Share to Bone Morphogenetic Proteins
Share to Cyclin-Dependent Kinase Inhibitor p21

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Dental Enamel

Share to Hedgehog Proteins

Share to Odontogenesis

Share to Organ Culture Techniques

Source

Identifiers

PMID: 16179481
DOI: 10.1126/science.1116848

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-16179481-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Regulation of mammalian tooth cusp patterning by ectodin.PMID 16179481Read ↗

On the difficulty of increasing dental complexity.Semantic proximity Read ↗

Notch Signaling Pathway in Tooth Shape Variations throughout Evolution.Semantic proximity Read ↗

Phenotypic and evolutionary implications of modulating the ERK-MAPK cascade using the dentition as a model.Semantic proximity Read ↗

A Suite of Mouse Reagents for Studying AmelogenesisSemantic proximity Read ↗

An FGF signaling loop sustains the generation of differentiated progeny from stem cells in mouse incisors.Semantic proximity Read ↗

The genetic basis of modularity in the development and evolution of the vertebrate dentition.Semantic proximity Read ↗

Disruption of Smad4 in odontoblasts causes multiple keratocystic odontogenic tumors and tooth malformation in mice.Semantic proximity Read ↗

Anomalous incisor morphology indicates tissue-specific roles for Tfap2a and Tfap2b in tooth development.Semantic proximity Read ↗

YAP overexpression affects tooth morphogenesis and enamel knot patterning.Semantic proximity Read ↗

Early epithelial signaling center governs tooth budding morphogenesis.Semantic proximity Read ↗

Three‐dimensional analysis of the early development of the dentitionSemantic proximity Read ↗

The development of archosaurian first-generation teeth in a chicken mutant.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.