Article

A Suite of Mouse Reagents for Studying Amelogenesis

2023-04-02

Abstract excerpt

<h4>SUMMARY</h4> Amelogenesis, the formation of dental enamel, is driven by specialized epithelial cells called ameloblasts, which undergo successive stages of differentiation. Ameloblasts secrete enamel matrix proteins (EMPs), proteases, calcium, and phosphate ions in a stage-specific manner to form mature tooth enamel. Developmental defects in tooth enamel are common in humans, and they can greatly impact the w...

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Literature Corpus work: 3677afee-ff9e-5a9e-ab8b-f59eaf545d5b
DOI: 10.1101/2023.03.30.534992

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