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Article

The dynamics of supernumerary tooth development are differentially regulated by Sprouty genes.

Journal of experimental zoology. Part B, Molecular and developmental evolution - 1 Jul 2013

Lagronova-Churava Svatava, Spoutil Frantisek, Vojtechova Simona, Lesot Herve, Peterka Miroslav, Klein Ophir D, Peterkova Renata

Abstract excerpt

In mice, a toothless diastema separates the single incisor from the three molars in each dental quadrant. In the prospective diastema of the embryo, small rudimentary buds are found that are presumed to be rudiments of suppressed teeth. A supernumerary tooth occurs in the diastema of adult mice carrying mutations in either Spry2 or Spry4. In the case of Spry2 mutants, the origin of the supernumerary tooth...

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PMID: 23606267
DOI: 10.1002/jez.b.22502

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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