Article
The Role of Epithelial Stat3 in Amelogenesis during Mouse Incisor Renewal.
Cells, tissues, organs - 1 Jan 2018
Zhang Bin, Meng Bo, Viloria Edward, Naveau Adrien, Ganss Bernhard, Jheon Andrew H
Abstract excerpt
The aim of this study was to evaluate the role of epithelial signal transducer and activator of transcription 3 (STAT3) in mouse incisor amelogenesis. Since Stat3 is expressed in the epithelial component of developing and adult mouse teeth, we generated and analyzed Krt14Cre/+;Stat3fl/fl mutant mice in which Stat3 was inactivated in epithelia including ameloblast progenitors and ameloblasts, the cells responsible...
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