Article
Association between tumor necrosis factor-alpha gene polymorphisms and prostate cancer risk: a meta-analysis.
Diagnostic pathology - 25 Mar 2014
Ma Liping, Zhao Jiangyang, Li Taijie, He Yu, Wang Jian, Xie Li, Qin Xue, Li Shan
Abstract excerpt
BACKGROUND: Tumor necrosis factor-alpha (TNF-α) is an important inflammatory cytokine that may play a role in controlling the progression of prostate cancer. Two common polymorphisms in the TNF-α gene, -308G/A and -238C/T, have been suggested to alter the risk for prostate cancer, but the results have been inconclusive so far. In order to obtain a better understanding of the effects of these two polymorphisms on...
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