Article
Polymorphisms in tumor necrosis factor-A gene and prostate cancer risk in North Indian cohort.
The Journal of urology - 1 Dec 2009
Kesarwani Pravin, Mandhani Anil, Mittal Rama Devi
Abstract excerpt
PURPOSE: The proinflammatory cytokine tumor necrosis factor-alpha has an important role in the pathogenesis of prostate cancer. Single nucleotide polymorphisms in the promoter region of the TNF-A gene alter tumor necrosis factor-alpha transcription. Thus, we studied the association of 4 SNPs in the promoter region of TNF-A gene, including -1031T>C, -863C>A, -857 C>T and -308 G>A, in a North Indian cohort of...
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