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Article

Genetic factors regulating inflammation and DNA methylation associated with prostate cancer.

Prostate cancer and prostatic diseases - 1 Mar 2013

Ianni M, Porcellini E, Carbone I, Potenzoni M, Pieri A M, Pastizzaro C D, Benecchi L, Licastro F

Abstract excerpt

BACKGROUND: Prostate cancer (PCa) displays a strong familiarity component and genetic factors; genes regulating inflammation may have a pivotal role in the disease. Epigenetic changes control chromosomal integrity, gene functions and ultimately carcinogenesis. The enzyme glycine-N-methyltransferase (GNMT) contributes to S-adenosylmethionine level regulation and, by affecting DNA methylation, influences gene...

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Share to alpha 1-Antichymotrypsin
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 22850906
DOI: 10.1038/pcan.2012.30

Genes

GNMT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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