Article
TNF polymorphisms and prostate cancer risk.
The Prostate - 1 Mar 2008
Danforth Kim N, Rodriguez Carmen, Hayes Richard B, Sakoda Lori C, Huang Wen-Yi, Yu Kai, Calle Eugenia E, Jacobs Eric J, Chen Bingshu E, Andriole Gerald L, Figueroa Jonine D, Yeager Meredith, Platz Elizabeth A, Michaud Dominique S, Chanock Stephen J, Thun Michael J, Hsing Ann W
Abstract excerpt
BACKGROUND: Inflammation has been hypothesized to increase prostate cancer risk. Tumor necrosis factor (TNF) is an important mediator of the inflammatory process, but the relationship between TNF variants and prostate cancer remains unclear. METHODS: We examined associations between six TNF single nucleotide polymorphisms (SNPs) (rs1799964, rs1800630, rs1799724, rs1800629, rs361525, ) and prostate cancer...