Article
Genetic variants of sex hormone-binding globulin and their biological consequences.
Molecular and cellular endocrinology - 5 Mar 2010
Xita Nectaria, Tsatsoulis Agathocles
Abstract excerpt
Several hormonal and metabolic factors have been found to influence the production of sex hormone-binding globulin (SHBG). In addition, twin studies have suggested that genetic factors may also contribute to variation in SHBG levels. Given the clinical significance of SHBG in regulating bioavailable sex steroid hormones, a number of studies examined the potential association between polymorphisms of SHBG gene and...
Topics
- Animals
- Genetic Variation
- Genotype
- Gonadal Steroid Hormones
- Humans
- Phenotype
- Polymorphism, Single Nucleotide
- Promoter Regions, Genetic
- Sex Hormone-Binding Globulin
