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Article

Concentration and genetic regulation of sex hormone binding globulin and fracture risk in older women.

Climacteric : the journal of the International Menopause Society - 1 Apr 2025

Wang Yuanyuan, Yu Chenglong, Islam Rakibul M, Hussain Sultana Monira, Barker Anna L, Lacaze Paul, McNeil John J, Davis Susan R

Abstract excerpt

OBJECTIVE: This study aimed to examine the association between concentrations of sex hormone binding globulin (SHBG) and fracture risk in community-dwelling older women and explore whether this was explained by the genetic regulation of SHBG. METHODS: This prospective cohort study examined 4871 women aged ≥70 years who were not taking medications influencing SHBG concentrations. A genome-wide association study...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 39636029
DOI: 10.1080/13697137.2024.2431036
PMCID: PMC11949721

Genes

SHBG

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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