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Article

Allele-specific deletions in mouse tumors identify Fbxw7 as germline modifier of tumor susceptibility.

PloS one - 1 Jan 2012

Perez-Losada Jesus, Wu Di, DelRosario Reyno, Balmain Allan, Mao Jian-Hua

Abstract excerpt

Genome-wide association studies (GWAS) have been successful in finding associations between specific genetic variants and cancer susceptibility in human populations. These studies have identified a range of highly statistically significant associations between single nucleotide polymorphisms (SNPs) and susceptibility to development of a range of human tumors. However, the effect of each SNP in isolation is very...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 22348067
DOI: 10.1371/journal.pone.0031301
PMCID: PMC3278431

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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