Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Meta-analysis of the brain-derived neurotrophic factor gene (BDNF) Val66Met polymorphism in anxiety disorders and anxiety-related personality traits.

Neuropsychobiology - 1 Jan 2008

Frustaci Alessandra, Pozzi Gino, Gianfagna Francesco, Manzoli Lamberto, Boccia Stefania

Abstract excerpt

OBJECTIVE: Brain-derived neurotrophic factor (BDNF) is potentially involved in the pathogenesis of anxiety. We carried out meta-analyses to evaluate the relationship between the BDNF Val66Met (valine, methionine) polymorphism and anxiety disorders (AD) or anxiety-related personality traits (ARPT). METHODS: Medline, Embase and PsycINFO were searched up to December 2007. We investigated 3 outcomes related to BDNF...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Anxiety
Share to Anxiety Disorders

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Brain-Derived Neurotrophic Factor

Share to Cross-Sectional Studies

Share to Genetic Heterogeneity

Share to Neuropsychological Tests

Share to Personality

Share to Surveys and Questionnaires

Source

Identifiers

PMID: 19088493
DOI: 10.1159/000182892

Genes

BDNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Meta-analysis of the brain-derived neurotrophic factor gene (BDNF) Val66Met polymorphism in anxiety disorders and anxiety-related personality traits.PMID 19088493Read ↗

Interaction between BDNF Val66Met and dopamine transporter gene variation influences anxiety-related traits.Semantic proximity Read ↗

Association of a functional BDNF polymorphism and anxiety-related personality traits.Semantic proximity Read ↗

BDNF serum levels, but not BDNF Val66Met genotype, are correlated with personality traits in healthy subjects.Semantic proximity Read ↗

Val66Met polymorphism in the brain-derived neurotrophic factor (BDNF) gene and its association with select anxiety-related disorders: an updated systematic review and meta-analysis.Semantic proximity Read ↗

The BDNF Val66Met polymorphism and anxiety: support for animal knock-in studies from a genetic association study in humans.Semantic proximity Read ↗

BDNF variation and mood disorders: a novel functional promoter polymorphism and Val66Met are associated with anxiety but have opposing effects.Semantic proximity Read ↗

5-HTTLPR genotype and anxiety-related personality traits: a meta-analysis and new data.Semantic proximity Read ↗

Brain derived neurotrophic factor gene Val66Met and -270C/T polymorphisms and personality traits predisposing to anorexia nervosa.Semantic proximity Read ↗

Association study of a brain-derived neurotrophic factor (Val66Met) genetic polymorphism and panic disorder.Semantic proximity Read ↗

Meta-analysis of the association between a serotonin transporter promoter polymorphism (5-HTTLPR) and anxiety-related personality traits.Semantic proximity Read ↗

Brain-Derived Neurotrophic Factor Val66Met Polymorphism Affects the Relationship Between an Anxiety-Related Personality Trait and Resting Regional Cerebral Blood Flow.Semantic proximity Read ↗

COMT and BDNF interacted in bipolar II disorder not comorbid with anxiety disorder.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.