Article
Brain derived neurotrophic factor gene Val66Met and -270C/T polymorphisms and personality traits predisposing to anorexia nervosa.
Neuro endocrinology letters - 1 Apr 2007
Rybakowski Filip, Dmitrzak-Weglarz Monika, Szczepankiewicz Aleksandra, Skibinska Maria, Slopien Agnieszka, Rajewski Andrzej, Hauser Joanna
Abstract excerpt
OBJECTIVES: Polymorphisms in BDNF gene has been proposed, as susceptibility loci for stress-related psychiatric disorders. Several lines of molecular and biochemical evidence point to the role of BDNF in anorexia nervosa (AN). Personality traits may constitute the intermediate phenotypes between genes and vulnerability to AN. METHODS: BDNF Val66Met and -270C/T polymorphisms were genotyped in 149 patients with AN...
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