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Article

COMT and BDNF interacted in bipolar II disorder not comorbid with anxiety disorder.

Behavioural brain research - 15 Jan 2013

Lee Sheng-Yu, Chen Shiou-Lan, Wang Yu-Shan, Chang Yun-Hsuan, Huang San-Yuan, Tzeng Nian-Sheng, Lee I Hui, Yeh Tzung Lieh, Yang Yen Kuang, Lu Ru-Band

Abstract excerpt

Bipolar disorder (BP), especially bipolar II disorder (BP-II), is highly comorbid with anxiety disorder (AD). Monoaminergic dysfunction has been implicated in the pathogenesis of BP, it may be important to investigate genes such as the catechol-O-methyltransferase (COMT), involved in monoamine metabolism and brain-derived neurotrophic factor (BDNF) genes, modulating the monoamine system. We therefore examined the...

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Source

Identifiers

PMID: 23026378
DOI: 10.1016/j.bbr.2012.09.039

Genes

BDNF
COMT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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