Article
Association of a functional BDNF polymorphism and anxiety-related personality traits.
Psychopharmacology - 1 Jun 2005
Lang Undine E, Hellweg Rainer, Kalus Peter, Bajbouj Malek, Lenzen Kirsten P, Sander Thomas, Kunz Dieter, Gallinat Jürgen
Abstract excerpt
RATIONALE: Converging lines of evidence point to brain-derived neurotrophic factor (BDNF) as a factor in the pathophysiology of depression. Recently, it was shown that the Val allele of the BDNF Val66Met substitution polymorphism showed a significant association with higher mean neuroticism scores of the NEO-Five Factor Inventory (NEO-FFI) in healthy subjects, and previous studies suggested the Val allele to be...
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