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Article

Interaction between BDNF Val66Met and dopamine transporter gene variation influences anxiety-related traits.

Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology - 1 Dec 2007

Hünnerkopf Regina, Strobel Alexander, Gutknecht Lise, Brocke Burkhard, Lesch Klaus Peter

Abstract excerpt

The involvement in neural plasticity and the mediation of effects of repeated stress exposure and long-term antidepressant treatment on hippocampal neurogenesis supports a critical role of brain-derived neurotrophic factor (BDNF) in the pathophysiology of affective and other stress-related disorders. A previously reported valine to methionine substitution at amino-acid position 66 (BDNF Val66Met) seems to account...

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Source

Identifiers

PMID: 17392738
DOI: 10.1038/sj.npp.1301383

Genes

BDNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Interaction between BDNF Val66Met and dopamine transporter gene variation influences anxiety-related traits.PMID 17392738Read ↗

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The BDNF gene Val66Met polymorphism as a modifier of psychiatric disorder susceptibility: progress and controversy.Semantic proximity Read ↗

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