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Article

Association study of a brain-derived neurotrophic factor (Val66Met) genetic polymorphism and panic disorder.

Neuropsychobiology - 1 Jan 2004

Lam Pok, Cheng Chih-Ya, Hong Chen-Jee, Tsai Shih-Jen

Abstract excerpt

Brain-derived neurotrophic factor (BDNF), a member of the neurotrophic factor family, plays an important role in the development, maintenance and function of several neuronal systems. Recent studies have demonstrated that antidepressants, commonly used for panic disorder treatment, can increase central BDNF. In addition, animals with BDNF deficits have higher levels of anxiety when exposed to stressors in...

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Identifiers

PMID: 15118353
DOI: 10.1159/000077362

Genes

BDNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Association study of a brain-derived neurotrophic factor (Val66Met) genetic polymorphism and panic disorder.PMID 15118353Read ↗

No association of the brain-derived neurotrophic factor (BDNF) gene polymorphisms with panic disorder.Semantic proximity Read ↗

Pathoclinical associations between panic disorders and the brain-derived neurotrophic factor Val66Met polymorphism: an updated meta-analysis.Semantic proximity Read ↗

Val66Met polymorphism in the brain-derived neurotrophic factor (BDNF) gene and its association with select anxiety-related disorders: an updated systematic review and meta-analysis.Semantic proximity Read ↗

No association between the brain-derived neurotrophic factor gene and panic disorder in Japanese population.Semantic proximity Read ↗

Association of a functional BDNF polymorphism and anxiety-related personality traits.Semantic proximity Read ↗

The Met allele of BDNF Val66Met polymorphism is associated with increased BDNF levels in generalized anxiety disorder.Semantic proximity Read ↗

Meta-analysis of the brain-derived neurotrophic factor gene (BDNF) Val66Met polymorphism in anxiety disorders and anxiety-related personality traits.Semantic proximity Read ↗

BDNF variant linked to anxiety-related behaviors.Semantic proximity Read ↗

Does BDNF Val66Met Polymorphism Confer Risk for Posttraumatic Stress Disorder?Semantic proximity Read ↗

The BDNF Val66Met polymorphism and anxiety: support for animal knock-in studies from a genetic association study in humans.Semantic proximity Read ↗

Gene×gene×gender interaction of BDNF and COMT genotypes associated with panic disorder.Semantic proximity Read ↗

Relationship between BDNF rs6265 (VAL66MET) polymorphism and serum BDNF LEVELS in anxiety disorders.Semantic proximity Read ↗

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