Article
Mitochondrial DNA haplogroups J and K are not protective for Parkinson's disease in the Australian community.
Movement disorders : official journal of the Movement Disorder Society - 30 Jan 2009
Mehta Prachi, Mellick George D, Rowe Dominic B, Halliday Glenda M, Jones Michael M, Manwaring Neil, Vandebona Himesha, Silburn Peter A, Wang Jie Jin, Mitchell Paul, Sue Carolyn M
Abstract excerpt
MtDNA haplogroups J and K have been associated with a decreased risk of developing Parkinson's disease (PD). To confirm this finding, we compared the distribution of mtDNA haplogroups J and K in a large sample of Australian patients with PD (n = 890) to population-based controls (n = 3,491). We assigned subjects to haplogroups J or K using standard PCR/RFLP techniques. Of the 890 subjects with PD, 10.6% were...
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