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Article

The EGFR signaling pathway controls gut progenitor differentiation during planarian regeneration and homeostasis.

Development (Cambridge, England) - 15 Jun 2016

Barberán Sara, Fraguas Susanna, Cebrià Francesc

Abstract excerpt

The planarian Schmidtea mediterranea maintains and regenerates all its adult tissues through the proliferation and differentiation of a single population of pluripotent adult stem cells (ASCs) called neoblasts. Despite recent advances, the mechanisms regulating ASC differentiation into mature cell types are poorly understood. Here, we show that silencing of the planarian EGF receptor egfr-1 by RNA interference...

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Source

Identifiers

PMID: 27122174
DOI: 10.1242/dev.131995

Genes

EGF
EGFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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