Article
The receptor tyrosine kinase gene linotte is required for neuronal pathway selection in the Drosophila mushroom bodies.
Mechanisms of development - 1 Nov 1998
Moreau-Fauvarque C, Taillebourg E, Boissoneau E, Mesnard J, Dura J M
Abstract excerpt
The linotte (lio) mutant was first isolated as a memory mutant. The lio gene encodes a putative receptor tyrosine kinase (RTK), homologous to the human protein RYK. This gene has been independently identified in a screen for embryonic nervous system axonal guidance defects and called derailed (drl). Here, we report that linotte mutants present structural brain defects in the adult central complex (CX) and...
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