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Article

KAP1-mediated epigenetic repression in the forebrain modulates behavioral vulnerability to stress.

Neuron - 10 Dec 2008

Jakobsson Johan, Cordero Maria Isabel, Bisaz Reto, Groner Anna C, Busskamp Volker, Bensadoun Jean-Charles, Cammas Florence, Losson Régine, Mansuy Isabelle M, Sandi Carmen, Trono Didier

Abstract excerpt

KAP1 is an essential cofactor of KRAB-zinc finger proteins, a family of vertebrate-specific epigenetic repressors of largely unknown functions encoded in the hundreds by the mouse and human genomes. Here, we report that KAP1 is expressed at high levels and necessary for KRAB-mediated repression i...

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Identifiers

PMID: 19081377
DOI: 10.1016/j.neuron.2008.09.036

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19081377-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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