Article
BAHD1 haploinsufficiency results in anxiety-like phenotypes in male mice.
PloS one - 1 Jan 2020
Pourpre Renaud, Naudon Laurent, Meziane Hamid, Lakisic Goran, Jouneau Luc, Varet Hugo, Legendre Rachel, Wendling Olivia, Selloum Mohammed, Proux Caroline, Coppée Jean-Yves, Herault Yann, Bierne Hélène
Abstract excerpt
BAHD1 is a heterochomatinization factor recently described as a component of a multiprotein complex associated with histone deacetylases HDAC1/2. The physiological and patho-physiological functions of BAHD1 are not yet well characterized. Here, we examined the consequences of BAHD1 deficiency in the brains of male mice. While Bahd1 knockout mice had no detectable defects in brain anatomy, RNA sequencing profiling...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.