Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The repertoire and dynamics of evolutionary adaptations to controlled nutrient-limited environments in yeast.

PLoS genetics - 1 Dec 2008

Gresham David, Desai Michael M, Tucker Cheryl M, Jenq Harry T, Pai Dave A, Ward Alexandra, DeSevo Christopher G, Botstein David, Dunham Maitreya J

Abstract excerpt

The experimental evolution of laboratory populations of microbes provides an opportunity to observe the evolutionary dynamics of adaptation in real time. Until very recently, however, such studies have been limited by our inability to systematically find mutations in evolved organisms. We overcome this limitation by using a variety of DNA microarray-based techniques to characterize genetic changes -- including...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Gene Deletion
Share to Genotype

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Molecular Sequence Data

Share to Mutation

Share to Phenotype

Share to Saccharomyces cerevisiae

Share to Saccharomyces cerevisiae Proteins

Share to Selection, Genetic

Source

Open in PubMed Open full text

Identifiers

PMID: 19079573
DOI: 10.1371/journal.pgen.1000303
PMCID: PMC2586090

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The repertoire and dynamics of evolutionary adaptations to controlled nutrient-limited environments in yeast.PMID 19079573Read ↗

Paths to adaptation under fluctuating nitrogen starvation: The spectrum of adaptive mutations in Saccharomyces cerevisiae is shaped by retrotransposons and microhomology-mediated recombination.Semantic proximity Read ↗

High-Throughput Identification of Adaptive Mutations in Experimentally Evolved Yeast Populations.Semantic proximity Read ↗

Molecular specificity, convergence and constraint shape adaptive evolution in nutrient-poor environments.Semantic proximity Read ↗

Challenges and potential solutions for studying the genetic and phenotypic architecture of adaptation in microbes.Semantic proximity Read ↗

Evolutionary dynamics and structural consequences of de novo beneficial mutations and mutant lineages arising in a constant environment.Semantic proximity Read ↗

Microbial laboratory evolution in the era of genome-scale science.Semantic proximity Read ↗

Experimental evolution of the model eukaryote Saccharomyces cerevisiae yields insight into the molecular mechanisms underlying adaptation.Semantic proximity Read ↗

Systematic changes in gene expression patterns following adaptive evolution in yeast.Semantic proximity Read ↗

The dynamics of diverse segmental amplifications in populations of Saccharomyces cerevisiae adapting to strong selection.Semantic proximity Read ↗

Molecular and cellular bases of adaptation to a changing environment in microorganisms.Semantic proximity Read ↗

Characteristic genome rearrangements in experimental evolution of Saccharomyces cerevisiae.Semantic proximity Read ↗

Use of adaptive laboratory evolution to discover key mutations enabling rapid growth of Escherichia coli K-12 MG1655 on glucose minimal medium.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.