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Article

Systematic changes in gene expression patterns following adaptive evolution in yeast.

Proceedings of the National Academy of Sciences of the United States of America - 17 Aug 1999

Ferea T L, Botstein D, Brown P O, Rosenzweig R F

Abstract excerpt

Culturing a population of Saccharomyces cerevisiae for many generations under conditions to which it is not optimally adapted selects for fitter genetic variants. This simple experimental design provides a tractable model of adaptive evolution under natural selection. Beginning with a clonal, founding population, independently evolved strains were obtained from three independent cultures after continuous aerobic...

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Identifiers

PMID: 10449761
DOI: 10.1073/pnas.96.17.9721
PMCID: PMC22277

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Source receipt: pubmed, retrieved 7 Sept 2026.

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