Microbial laboratory evolution in the era of genome-scale science.

Abstract excerpt

Laboratory evolution studies provide fundamental biological insight through direct observation of the evolution process. They not only enable testing of evolutionary theory and principles, but also have applications to metabolic engineering and human health. Genome-scale tools are revolutionizing studies of laboratory evolution by providing complete determination of the genetic basis of adaptation and the changes...

Topics

• Adaptation, Physiological
• Escherichia coli
• Evolution, Molecular
• Gene Expression Regulation, Bacterial
• Genome, Bacterial
• Models, Molecular
• Mutation
• Phenotype