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Article

Assessing departure from Hardy-Weinberg equilibrium in the presence of disease association.

Genetic epidemiology - 1 Nov 2008

Li Mingyao, Li Chun

Abstract excerpt

Assessing Hardy-Weinberg equilibrium (HWE) is often employed as an important initial step for genotype data quality checking in genetics studies. Tests for HWE often assume that the genotypes are randomly sampled from the general population. However, in many human genetics studies, subjects are ascertained through their disease status, and affected individuals (and their relatives in family-based studies) are...

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PMID: 18449919
DOI: 10.1002/gepi.20335

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

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