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Article

Rational inferences about departures from Hardy-Weinberg equilibrium.

American journal of human genetics - 1 Jun 2005

Wittke-Thompson Jacqueline K, Pluzhnikov Anna, Cox Nancy J

Abstract excerpt

Previous studies have explored the use of departure from Hardy-Weinberg equilibrium (DHW) for fine mapping Mendelian disorders and for general fine mapping. Other studies have used Hardy-Weinberg tests for genotyping quality control. To enable investigators to make rational decisions about whether DHW is due to genotyping error or to underlying biology, we developed an analytic framework and software to determine...

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Identifiers

PMID: 15834813
DOI: 10.1086/430507
PMCID: PMC1196455

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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