Article
Mechanism of action of a dominant-negative mutant of c-Jun.
Oncogene - 1 Mar 1994
Brown P H, Chen T K, Birrer M J
Abstract excerpt
The AP-1 transcriptional activating complex, made up of Jun and Fos protein, is involved in controlling many cellular processes such as cell proliferation, differentiation and transformation. We have previously characterized a dominant-negative mutant of c-Jun called TAM-67 which forms dimers wit...
Topics
- Animals
- Cell Line
- DNA-Binding Proteins
- Female
- Fungal Proteins
- Gene Expression Regulation
- Genes, Dominant
- Leucine Zippers
- Mutation
- Protein Binding
- Protein Kinases
- Proto-Oncogene Proteins c-fos
- Proto-Oncogene Proteins c-jun
- Rats
- Rats, Inbred F344
- Recombinant Fusion Proteins
- Saccharomyces cerevisiae Proteins
- Sequence Deletion