Article
Cell-type specific multiprotein complex formation over the c-fos serum response element in vivo: ternary complex formation is not required for the induction of c-fos.
Nucleic acids research - 11 Jul 1991
König H
Abstract excerpt
At the serum response element (SRE) of the c-fos proto-oncogene a ternary complex with two proteins, ternary complex factor (p62TCF) and serum response factor (SRF) can be formed. Its formation has previously been suggested to be necessary for efficient induction of c-fos transcription by serum in mouse NIH 3T3 fibroblasts (1) and by phorbol esters, but not by serum, in mouse BALB/c 3T3 fibroblasts (2). It is...
Topics
- Animals
- Base Sequence
- Blood Proteins
- Cells, Cultured
- DNA-Binding Proteins
- Gene Expression Regulation
- Macromolecular Substances
- Mice
- Molecular Sequence Data
- Multiprotein Complexes
- Mutation
