Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Phosphorylation-dependent formation of a quaternary complex at the c-fos SRE.

Molecular and cellular biology - 1 Mar 1996

Gille H, Kortenjann M, Strahl T, Shaw P E

Abstract excerpt

The rapid and transient induction of the human proto-oncogene c-fos in response to a variety of stimuli depends on the serum responses element (SRE). In vivo footprinting experiments show that this promoter element is bound by a multicomponent complex including the serum response factor (SRF) and a ternary complex factor such as Elk-1. SRF is thought to recruit a ternary complex factor monomer into an asymmetric...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Base Sequence
Share to DNA-Binding Proteins
Share to Mice

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Molecular Sequence Data

Share to Mutation

Share to Nuclear Proteins

Share to Protein Conformation

Share to Transcription Factors

Source

Open in PubMed Open full text

Identifiers

PMID: 8622654
DOI: 10.1128/MCB.16.3.1094
PMCID: PMC231092

Genes

SRF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Phosphorylation-dependent formation of a quaternary complex at the c-fos SRE.PMID 8622654Read ↗

Sequences at the 3' side of the c-fos SRE mediate gene expression via an Sob1-dependent, TCF-independent pathway.Semantic proximity Read ↗

Novel roles of specific isoforms of protein kinase C in activation of the c-fos serum response element.Semantic proximity Read ↗

The inner core of the serum response element mediates both the rapid induction and subsequent repression of c-fos transcription following serum stimulation.Semantic proximity Read ↗

Identification of multiple SRF N-terminal phosphorylation sites affecting DNA binding properties.Semantic proximity Read ↗

Ternary complex factor-serum response factor complex-regulated gene activity is required for cellular proliferation and inhibition of apoptotic cell death.Semantic proximity Read ↗

ERK2- and p90(Rsk2)-dependent pathways regulate the CCAAT/enhancer-binding protein-beta interaction with serum response factor.Semantic proximity Read ↗

Activation of the human T-cell leukemia virus type 1 long terminal repeat by the ternary complex factor Elk-1.Semantic proximity Read ↗

Regulation of c-Fos gene transcription by stimulus-responsive protein kinases.Semantic proximity Read ↗

Cell-type specific multiprotein complex formation over the c-fos serum response element in vivo: ternary complex formation is not required for the induction of c-fos.Semantic proximity Read ↗

The Fes tyrosine kinase: a signal transducer that regulates myeloid-specific gene expression through transcriptional activationSemantic proximity Read ↗

CCAAT/enhancer binding protein epsilon: changes in function upon phosphorylation by p38 MAP kinase.Semantic proximity Read ↗

ERK-Induced Activation of TCF Family of SRF Cofactors Initiates a Chromatin Modification Cascade Associated with Transcription.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.