Article
Phosphorylation-dependent formation of a quaternary complex at the c-fos SRE.
Molecular and cellular biology - 1 Mar 1996
Gille H, Kortenjann M, Strahl T, Shaw P E
Abstract excerpt
The rapid and transient induction of the human proto-oncogene c-fos in response to a variety of stimuli depends on the serum responses element (SRE). In vivo footprinting experiments show that this promoter element is bound by a multicomponent complex including the serum response factor (SRF) and a ternary complex factor such as Elk-1. SRF is thought to recruit a ternary complex factor monomer into an asymmetric...
Topics
- Animals
- Base Sequence
- DNA-Binding Proteins
- Gene Transfer Techniques
- Mice
- Molecular Sequence Data
- Mutation
- Nuclear Proteins
- Protein Conformation
- Proto-Oncogene Mas
- Proto-Oncogene Proteins
- Proto-Oncogene Proteins c-fos
- Serum Response Factor
- Transcription Factors
- ets-Domain Protein Elk-1
