Article
Dopamine D2 receptor polymorphisms and adenoma recurrence in the Polyp Prevention Trial.
International journal of cancer - 1 May 2009
Murphy Gwen, Cross Amanda J, Sansbury Leah S, Bergen Andrew, Laiyemo Adeyinka O, Albert Paul S, Wang Zhuoqiao, Yu Binbing, Lehman Teresa, Kalidindi Aravind, Modali Rama, Schatzkin Arthur, Lanza Elaine
Abstract excerpt
Epidemiological evidence suggests that obesity may be causally associated with colorectal cancer. Dopamine and the dopaminergic reward pathway have been implicated in drug and alcohol addiction as well as obesity. Polymorphisms within the D2 dopamine receptor gene (DRD2) have been shown to be ass...
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