Article
Genetic polymorphisms in vitamin D receptor VDR/RXRA influence the likelihood of colon adenoma recurrence.
Cancer research - 15 Feb 2010
Egan Jan B, Thompson Patricia A, Ashbeck Erin L, Conti David V, Duggan David, Hibler Elizabeth, Jurutka Peter W, Leroy Elizabeth C, Martínez María Elena, Mount David, Jacobs Elizabeth T
Abstract excerpt
Low circulating levels of vitamin D affect colorectal cancer risk. The biological actions of the hormonal form of vitamin D, 1,25(OH)(2)D(3), are mediated by the vitamin D receptor (VDR), which heterodimerizes with retinoid X receptors (RXR). Using a single nucleotide polymorphism (SNP) tagging a...
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