Article
Vitamin D, calcium supplementation, and colorectal adenomas: results of a randomized trial.
Journal of the National Cancer Institute - 3 Dec 2003
Grau Maria V, Baron John A, Sandler Robert S, Haile Robert W, Beach Michael L, Church Timothy R, Heber David
Abstract excerpt
BACKGROUND: Calcium and vitamin D both appear to have antineoplastic effects in the large bowel. Although these nutrients are inter-related metabolically in bone and in the normal intestine, their potential interactions in large-bowel carcinogenesis are not well understood. METHODS: We assessed independent and joint effects of calcium supplementation and vitamin D status on adenoma recurrence in 803 subjects in a...
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