Article
Alcohol consumption, variability in alcohol dehydrogenase genes and risk of renal cell carcinoma.
International journal of cancer - 15 Feb 2018
Antwi Samuel O, Eckel-Passow Jeanette E, Diehl Nancy D, Serie Daniel J, Custer Kaitlynn M, Wu Kevin J, Cheville John C, Thiel David D, Leibovich Bradley C, Parker Alexander S
Abstract excerpt
Alcohol consumption has been associated inversely with renal cell carcinoma (RCC) risk; however, no study has examined effect modification by germline variation in alcohol-metabolizing genes. We investigated whether the association between alcohol intake and RCC risk is modulated by germline variants in alcohol dehydrogenase genes in a large case-control study. Data from 652 RCC cases and 1,366 non-cancer...
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