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Article

HOXA9 is required for survival in human MLL-rearranged acute leukemias.

Blood - 12 Mar 2009

Faber Joerg, Krivtsov Andrei V, Stubbs Matthew C, Wright Renee, Davis Tina N, van den Heuvel-Eibrink Marry, Zwaan Christian M, Kung Andrew L, Armstrong Scott A

Abstract excerpt

Leukemias that harbor translocations involving the mixed lineage leukemia gene (MLL) possess unique biologic characteristics and often have an unfavorable prognosis. Gene expression analyses demonstrate a distinct profile for MLL-rearranged leukemias with consistent high-level expression of select Homeobox genes, including HOXA9. Here, we investigated the effects of HOXA9 suppression in MLL-rearranged and...

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Share to Histone-Lysine N-Methyltransferase
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 19056693
DOI: 10.1182/blood-2007-09-113597
PMCID: PMC2656267

Genes

HOXA9
HOXA10
MEIS1
PBX3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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HOXA9 is required for survival in human MLL-rearranged acute leukemias.PMID 19056693Read ↗

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